What are the passivation properties of the ibidi Bioinert surface?

The Bioinert surface is a thin polyol hydrogel layer that is covalently bound to the ibidi Polymer Coverslip Bottom of the µ-Slide. It does not allow any cells or biomolecules to bind to the surface, which makes it superior to standard ultra-low attachment (ULA) products.

The stable passivation is maintained for days, or even weeks, which is especially important during long-term experiments. Furthermore, high-resolution microscopy is guaranteed with the flat, thin bottom material and the excellent optical properties of the ibidi Polymer Coverslip. They are the ideal solution if you want to culture cells or cell aggregates without any adhesion to the surface (e.g., suspension cells, spheroids, and embryoid bodies).

For controlled cell adhesion, ibidi has also launched µ-Slides with µ-Patterns, which have defined adhesion spots surrounded by Bioinert. Adherent cells from a suspension are caught by these spots, leading to spatially controlled cell adhesion.

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