The Endothelial Cell
Angiogenesis plays an essential role in the processes of:
- Tumor growth
- Vascularization (formation of new blood vessels with endothelial cells to feed the tumor)
- Chemotactically recruitment of blood vessel cells towards the tumor
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Research on cell barrier function in drug research, pharmacology, oncology, cancer, or toxicology
Examples are:
- blood-brain barrier
- cell-cell contacts
- cell junctions
ibidi Products used for this Application:
Long-term cell cultivation of cells under flow conditions for the analysis of
- polarization
- protein expression
- morphology or
- other changes of the cell under defined shear stress
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Inflammation processes include:
- Interaction of immune cells (e.g., leucocytes) with blood
- Rolling and adhesion of vessel cells
- Transmigration, i.e. moving of, for example, cancer cells through the endothelium
- Directed movement (chemotaxis) by attraction of immune cell
ibidi Products used for this Application: