International Cell Culture Under Flow Meeting 2024

July 24–25, 2024 | Northwestern University, Chicago, IL, USA

This meeting took place in the past, the registration is closed.

Date:	July 24–25, 2024	Download Abstract Book
Location:	Northwestern University, Chicago, IL, USA
Organizers:	Luisa Arispe, Northwestern University, Chicago, IL, USA Roman Zantl, ibidi, Munich, Germany
Contact:	E-mail: flowmeeting2024@ibidi.com Phone USA: (844) 276-6363 Phone International: +49 89 520 46 17-0

Focus of the Meeting Confirmed Speakers Program How to Get There Payment Information

Focus of the Meeting

The second international “Cell Culture Under Flow” meeting will bring together scientists from a variety of fields (e.g., vascular research, immunology, barrier function), who cultivate cells under shear stress.

Participants will have the chance to present their most recent work. In addition, both young and experienced scientists will have the opportunity to network and discuss future objectives of this field of research. Abstracts will be selected for oral presentation and posters.

Confirmed Speakers

• Hanjoong Jo (Georgia Tech and Emory University, USA)
• Jan Kitajewski (University of Illinois, USA)
• Julia Mack (University of California Los Angeles, USA)
• Matthew Kutys (University of California San Francisco, USA)
• Paul Evans (Queen Mary University of London, United Kingdom)
• Simone Bergmann (Technical University Braunschweig, Germany)
• Tatiana Petrova (University of Lausanne, Switzerland)
• Yun Fang (University of Chicago, USA)

Impressions of the Previous Meeting

Program

July 24

Registration and Reception
8:30 am		Registration
Welcome and Keynote Lecture
9:30–10:15 am		Chair: Roman Zantl (ibidi GmbH, GER)
9:30 am	10 min	Welcome: Luisa Iruela-Arispe (Northwestern University, USA) / Roman Zantl (ibidi GmbH, GER)
9:40 am	30 + 5 min	Keynote: Flow-Induced Endothelial Polarity Luisa Iruela-Arispe (Northwestern University, USA)
Session 1:  Microvascular Morphogenesis
10:15–11:05 am		Chair: Roman Zantl (ibidi GmbH, GER)
10:15 am	30 + 5 min	Keynote: Coordination of Vascular Morphogenesis at Endothelial Cell-Cell Interfaces	Matthew Kutys (University of California San Francisco, USA)
10:50 am	10 + 5 min	Oscillatory Shear Stress Modulates Lymphatic Progenitor Cells Maturation Into Lymphatic Vessels With Anti-Cancer Phenotypes	Nancy Lightsey (University of Notre Dame, USA)
11:05 am	35 min	Coffee break
Session 2:  Mechanotransduction
11:40 am–1:00 pm		Chair: Paul Evans (Queen Mary University of London, UK)
11:40 am	30 + 5 min	Keynote: Flow-Mediated Mechanisms of Endothelial Cell Resilience	Julia Mack (University of California Los Angeles, USA)
12:15 pm	10 + 5 min	Low Shear in Short-Term Impacts Endothelial Cell Traction and Alignment in Long-Term Under High Shear	Sangyoon Han (Michigan Technological University, USA)
12:30 pm	10 + 5 min	Mechanotransduction via Endothelial Adhesion Molecule CD31 Initiates Transmigration and Reveals a Role for VEGFR2 in Diapedesis	Bill Muller (Northwestern University, USA)
12:45 pm	10 + 5 min	CD36-Mediated Lipid Uptake Mediates Endothelial Stiffening Under Disturbed Flow and in Aortic Arch	Victor Aguilar (University of Illinois, USA)
1:00 pm	60 min	Lunch break
Session 3:  Molecular Mechanisms of Shear Stress Response
2:00–3:20 pm		Chair: Tatiana Petrova (University of Lausanne, CH)
2:00 pm	30 + 5 min	Keynote: Understanding Endothelial Cell Responses to Flow Through Study of Notch Target Genes	Jan Kitajewski (University of Illinois, USA)
2:35 pm	10 + 5 min	Notch Signaling Regulates Unc5B to Suppress Endothelial Proliferation and Branching and to Support Junction Formation and Polarization in Response to Flow	L.A. Naiche (University of Illinois, USA)
2:50 pm	10 + 5 min	Flow-sensitive Endothelial K+ Channels are Master Regulators of Endothelial Mechanotransduction and Gene Expression	Sang Joon Ahn (University of Illinois, USA)
3:05 pm	10 + 5 min	Dissection of Endothelial Junctional Dynamics Following Angiogenic Stimulation Through Application of an Engineered Optogenetic Biotin Ligase	Nicholas Leschinsky (University of Illinois, USA)
ibidi Industry Talk
3:25–4:00 pm		Industry Talk: Future Technologies and Applications for Cell Culture Under Flow	Nina Huber (ibidi GmbH, GER)
Poster Session
4:00–8:00 pm		Poster Session With Snacks and Drinks

July 25

Session 4:  Atherosclerosis
9:00–10:40 am		Chair: Julia Mack (University of California Los Angeles, USA)
9:00 am	30 + 5 min	Keynote: Endothelial Responses to Flow in Atherosclerosis	Paul Evans (Queen Mary University of London, UK)
9:35 am	30 + 5 min	Keynote: Flow-Sensitive HEG1 Regulates Endothelial Function and Protects Against Atherosclerosis	Hanjoong Jo (Georgia Tech and Emory University, USA)
10:10 am	10 + 5 min	MicroRNA Deregulation as the Mechanism of Cadmium-Induced Atherosclerosis	Abeer Mohamed (University of Illinois, USA)
10:25 am	10 + 5 min	Mechanosensitive Protein FHL2 Tunes Endothelial Flow Response	Shailaja Seetharaman (The University of Chicago, USA)
10:40 am	30 min	Coffee break
Session 5:  Renewal and Repair
11:10 am–1:05 pm		Chair: Yun Fang (The University of Chicago, USA)
11:10 am	30 + 5 min	Keynote: Mechanisms of Lymphatic Vessel Renewal and Repair	Tatiana Petrova (University of Lausanne, CH)
11:45 am	30 + 5 min	Keynote: Effect of Microfluidic on Endothelial Wound Regeneration During Streptococcal Infection	Simone Bergmann (Technical University Braunschweig, DE)
12:20 pm	10 + 5 min	Electro-Osmotic Flow Directs Cell Migration and Growth of Endothelial Sprouts	Mark Messerli (South Dakota State University, USA)
12:35 pm	10 + 5 min	Enhancing the Targeting Efficacy of Endothelial Colony Forming Cells for Renal Regeneration via Kidney-Targeted Liposomal Nanoparticles	Brenda Cruz-Gonzalez (University of Notre Dame, USA)
12:50 pm	10 + 5 min	Shear-Sensitive Notch Activation via Extracellular Vesicles to Treat Vascular Injuries	Prerak Gupta (University of Illinois, USA)
1:05 pm	55 min	Lunch break
Session 6:  Mechanotherapeutics, Cancer, Inflammation
2:00–3:35 pm		Chair: Luisa Iruela-Arispe (Northwestern University, USA)
2:00 pm	30 + 5 min	Keynote: Vascular Mechanobiology and Mechano- therapeutics	Yun Fang (The University of Chicago, USA)
2:35 pm	10 + 5 min	Disturbed Flow Induces Reprogramming of Endothelial Cells to Immune-Like and Foam Cells Under Hypercholesterolemia During Atherogenesis	Christian Park (Emory University & Georgia Tech, USA)
2:50 pm	10 + 5 min	Mechano-Sensitive ER Protein TXNDC5 Promotes Neointimal Hyperplasia of Arterio-Venous Fistula Through Endothelial-Mesenchymal Transition and eNOS Suppression	Chih-Fan Yeh (National Taiwan University Hospital, TW)
3:05 pm	10 + 5 min	The Role of Endothelial Ackr1 in Breast Cancer Metastasis	S. Tanner Roach (University of Illinois, USA)
3:20 pm	10 + 5 min	Endothelial Caveolin-1 and CXCL10 Promote Transcellular Migration of Autoreactive T Cells Across the Blood-Brain Barrier	Ali A. Almousawi (University of Illinois, USA)
Closing Remarks and Young Scientist Award
3:35–4:00 pm		Luisa Iruela-Arispe (Northwestern University, USA) / Roman Zantl (ibidi GmbH, GER)
3:35 pm	10 min	Young Scientist Award
3:45 pm	10 min	Closing Remarks

Download Abstract Book

How to Get There

Meeting location: Simpson Querrey Building, Main Atrium, Ground Floor, 303 E Superior St, Chicago, IL 60611, USA

Public parking: Erie Ontario Self Park, 321 E Erie St, Chicago, IL 60611

Directions from parking: Exit the parking ramp on E Erie St and turn left (west). Walk to N Fairbanks Ct and turn right (north). In one block you will reach the Simpson Querrey Building, which is between E Huron St and E Superior St on N Fairbanks Ct. There are entrances to the building on both Huron (south entrance) and Erie (north entrance) and both entrances lead to the main atrium, where the conference will be held.

Additional parking: Northwestern Garage, 222 East Huron Street, Chicago, IL 60611

Payment Information

The entry fee will cover entry to all sessions, as well as snacks during breaks.

PLEASE NOTE: Your registration is not valid or complete until this payment has been received, unless other arrangements have been made. There will be no refunds.

Date:	July 24–25, 2024	Download Abstract Book
Location:	Northwestern University, Chicago, IL, USA
Organizers:	Luisa Arispe, Northwestern University, Chicago, IL, USA Roman Zantl, ibidi, Munich, Germany
Contact:	E-mail: flowmeeting2024@ibidi.com Phone USA: (844) 276-6363 Phone International: +49 89 520 46 17-0