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Join Us for Our 11th ibiTea on May 15, 2024:

Spheroid-on-Chip: Unraveling the Impact of Fluid Dynamics on Mesenchymal Stem Cell Spheroids

Dr. Apurva Mishra, Faculty of Dentistry, National University of Singapore

We cordially invite you to our 11th ibiTea webinar. Join us for an informative webinar on the latest techniques for tissue regeneration. A leading scientist in the field of dentistry will discuss the latest advancements in stem cell biology and how microfluidics can affect the cultivation and differentiation of stem cells in a spheroid-on-chip model.

Are you interested in participating in this ibiTea? If so, grab a cup of tea and join our scientific discussion on:

May 15, 2024, 10 am Munich CEST
(4 pm Singapore SGT |4 pm Taiwan CST | 5 pm Tokyo JST)

Register Now

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The number of participants is limited, so please reserve your spot today.

ibiTea Topic Outline

In the 11th ibiTea, Apurva Mishra will discuss the impact of microfluidics on the growth and differentiation of stem cells in a spheroid-on-chip model.

Specifically, the talk will focus on the effects of fluid flow on tooth-derived mesenchymal stem cells (MSCs) within a spheroid-on-chip microperfusion array. The investigation highlights the influence of fluid dynamics on the viability of MSCs within the spheroids and their ability to form bone-like tissue. The potential to control the spatio-temporal differentiation of MSCs within the spheroids by manipulating flow conditions is demonstrated, providing new insights for periodontal and bone regenerative therapies.

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Representative confocal z-sections of spheroids after 14 days of culture under osteodifferentiation medium and stained with calcium-binding agent BoneTag (red) and DAPI (blue). The panels represent superficial and deeper z-sections of the spheroids to visualize the calcium deposits within peripheral and deeper zones (scale bar: 100 µm).

Speaker

Dr. Apurva Mishra
Faculty of Dentistry, National University of Singapore

Apurva Mishra is a trained pediatric dentist who is currently a Ph.D. candidate at the National University of Singapore Faculty of Dentistry. His research is centered around cutting-edge tissue regeneration techniques utilizing the latest advancements in stem cell biology, biomaterials, and microfluidics.

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