A morphological biosensor used to measure cell behavior which employs a label-free, non-invasive method to electronically monitor cells grown in tissue culture
- Non-invasive cell-based assays in culture medium
- Measurement of changes in cell morphology
- Multiple, real-time measurements
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|71616||ECIS Model Z: ECIS Model Z station controller, Elevated Field Module (i.e., a pulse system for automated wound healing or electroporation studies), software for data gathering and analysis, laptop||1|
|71617||ECIS Model Z Theta: ECIS Model Z Theta station controller, Elevated Field Module (i.e., a pulse system for automated wound healing or electroporation studies), software for data gathering and analysis, including model calculations, laptop||1|
|71612||ECIS 16 Well Station: a holder with two slots for ECIS Cultureware 8 well arrays, and a data processing station||1|
|71614||ECIS 96 Well Station: a holder with one slot for ECIS Cultureware 96 well arrays, and a data processing station||1|
|71621||Upgrade ECIS 96 Well Station: upgrade to bed of nails on 96 well array station||1|
|71001||ECIS Flow Module: perfusion system for ECIS flow arrays, ideal for defined flow rates and shear stress studies of endothelial cells||1|
|71609||ECIS Transwell Measurement System: permanent transwell holder to run TEER measurements. Made for filter-based assays. Contains a lower Filter holder base and an upper counter electrode system, reusable||1|
Cells grown on an ECIS electrode
The ECIS method represents a non-invasive approach to monitor living cells in vitro. It measures the change in impedance of a small electrode over time.
In this system, cells are grown on small gold film electrodes carrying very weak AC signals. As cells attach and spread on these electrodes, their insulating membranes block and constrain the current flow, resulting in measured variations in the electrode impedance. Any changes in the environment, leading to morphological changes of the cell, alter the current paths and can be readily detected by the instrumentation. These changes may be due to the addition of compounds, changes in the physical environment (for example perfusion, transfection events, viral infections, and the addition of other cells).
The ECIS Cultureware consists of disposable electrode arrays containing gold film electrodes. Click here to learn more about the various types of ECIS Cultureware.
For further information please contact us.
For more than 800 scientific publications using the ECIS technology please visit www.biophysics.com.
Impedance Measurements Under Flow Conditions
For impedance measurements under flow conditions, combine the ECIS System with the Pump System to more closely simulate the in vivo environment.
ECIS Transwell Measurement System
This system is designed to measure the TEER (Trans Epithelial / Endothelial Electric Resistance) of cell layers grown on filter inserts.
The ECIS Transwell Measurement System is a permament transwell holder to measure the TEER of cell layers. The holder contains a lower Filter holder base and an upper counter electrode system. It is used in filter-based assays.