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Impedance Based Wound Healing Assays
using ECIS

With ECIS’s impedance measurements, functional wound healing assays can be performed with unrivaled convenience. After wounding cells on an electrode with an electric pulse, ECIS’s label-free impedance measurement technology allows the user to measure the wound healing process in real time. ECIS standard 96 well screening plates are designed for high-throughput applications, such as migration inhibitors screening.

The general effects of enhancers and inhibitors on wound healing are provided below, along with typical data from migration inhibitors screenings.

ECIS impedance assays are label free and are performed under real-time conditions, inside incubators.

Typical Migration Data Obtained Using ECIS Technology

The emptied electrode is re-covered with cells after 14 hours. The graph shows that different inhibitors slow down the wound healing process.